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Impotence is men’s inability to achieve or maintain an erection sufficient for sexual intercourse. It includes the failure to get an erection as a result of sexual stimulation or to lose your erection prior to ejaculation. Types of impotence Arteriogenic impotence: The arteries supply blood to the penis. When arteries narrow, they fail to bring in sufficient blood to the penis resulting in erectile dysfunction. It mainly occurs in elderly people. Those who are diabetic or have high blood pressure are also prone to it. Arteriogenic impotence due to injuries is common but often goes unnoticed because of ignorance. Later the injured discovers it and seeks medical help. Venogenic impotence: During erection, the veins of the penis close down in a normal individual. This hardens the penis assisting a complete erection. But when the veins leak blood, the penis fails to sustain an erection thus leading to Venogenic impotence. It is the most common form, which accounts to 30-70% of impotence. Neurogenic impotence: The nerve supply to the penis is sensitive and complicated. These nerves control the arteries and veins, which change the blood flow within the penis. An injury to the back or other nerves related to the penis can cause Neurogenic impotence. Many operations on the rectum, prostrate, urethra, spine and urinary bladder are performed for improving the performance. Impotence from Diabetes Mellitus: Impotence is very common among diabetics. A study showed around 50% of diabetics as patients of male impotence. Endocrinologic impotence: When there is an imbalance of sex hormones in the blood stream, erection doesn’t occur. Nearly 5 to 10% of men suffer from Endocrinologic impotence. Mixed impotence: More than one factor can cause impotence in men. It could be physical factors as well as psychological factors. Mixed impotence refers to this form of impotence. Psychogenic impotence: Sometimes, the problem lies entirely in the mind. There will be no physical factors accompanying erectile dysfunction. This is a state of Psychogenic impotence. People often undergo bouts of depression and anxiety. See a doctor if you have difficulty in attaining or maintaining an erection. The earlier you find out, the easier it becomes to diagnose and treat. penis enlagement traction device enlargement penis pill vimax penis enargement surgery picture homemade penis enargement vimax do penis enlargement pills work penis enargement pic herbal penis enargement vimax penis enlargement operation
Hey Viagra users! Do you know how your magic pill works on you? Hmmm…forgotten right! Or are you ignorant about its mechanism? Whatever, am sure about one thing you were startled after reading the title of this write-up! To understand Viagra mechanism we need to first understand how one gets a penis erection. Penile erection process is initiated with sexual excitement. The stimulation generates electrical impulses in the brain and sends it to the nerves going to the penile section. The nerve then releases nitric oxide to increase the production of cyclic GMP in muscle cells of corpus cavernosum simultaneously. Nitric oxide smoothes the muscles and increases the size of the blood vessels allowing high-speed blood flow to the penis. As a result the penis is engorged with blood making it firm and strong for penetrative sex. So what we understand from this is that the level of NO (Nitric oxide) is mainly responsible for giving a strong penile erection. Viagra does not have any direct relaxant effect on the penile section but it enhances the effect of nitric oxide by inhibiting phosphodiesterase type 5 (PDE5). When sexual stimulation leads to the release of Nitric oxide, the inhibition of PDE5 by Viagra causes increased levels of cyclic guanosine monophosphate which gives muscle relaxation and blood inflow to the corpus cavernosum which ultimately helps in getting the required erections of the penis. Now, I am sure you will be able to relate the Nobel Prize winner Dr. Furchgott with Viagra and its functioning. Nitric oxide was initially known as Endothelial Derived Relaxing Factor (EDRF), ERDF was released, when patients took the nitrate-type blood pressure medicines popular in the 1970s and 1980s, and in turn it caused relaxation of the smooth muscles around the blood vessels and the arteries became larger, allowing better blood flow and a lower blood pressure. In 1986, Dr. Furchgott identified the EDRF as nitric oxide. This is where the Viagra makers got the idea of a magic pill for sex which revolutionized the whole idea of impotence. They noticed from the research that the nitrate drugs had certain side-effects on the blood vessels and the arteries; relaxing the smooth muscles around the blood vessels thereby increasing the blood flows in the human body. They related it to the erectile anatomy and discovered Sildenafil citrate, a chemical that inhibited PDE5 inhibitors which is responsible for the level of NO (nitric oxide) in the penile section. Sildenafil Citrate, under the brand name of Viagra, became the pioneer pill for the treatment of erectile dysfunction and received FDA approval on March 27, 1998, the rest is history! After all a better blood flow is the key factor behind a strong erection. So the master mind behind Viagra, in a way, remains Dr. Furchgott, the inventor of nitric oxide. Without the knowledge of the existence of nitric oxide, no one could think of inhibiting phosphodiesterase type 5 to maintain the level of NO to get penis erection. Let’s toast for the good health of Dr. Furchgott and congratulate him on winning the Nobel Prize. Without his discoveries Viagra would not have been possible and millions of men with erectile dysfunction would have continued to live hopelessly and helplessly as ‘ashamed impotents’. Thanks Dr. Furchgott for everything you have given us through your discovery! penile enlargement tip homemade penis enlargment herbal penis enargement pills penile enlargement stretcher free exercise tip for penile enlargment herbal penis elargement pills medical penile enlargement vigrx penis pill penis enhancement tip
Most men have been there at one time or another. That moment when total sexual exhilaration turns to pure panic and fear...fear that the "little astronaut" out on his moon walk has lost his space suit. Fear that the knight is no longer wearing his shining armor. The number one reason that condoms break or slip off during the horizontal mambo is that the Johnson in question was not properly suited. Like shoes or bras, careful consideration must be given to condom size. Yes, all men are created equal — but in very different shapes and sizes when it comes to the trouser department. And while it may not be the size of the wave that floats your boat, when it comes to choosing a condom, your size does matter. RESEARCHERS AGREE A recent survey by Durex Condoms revealed that the length of an erect penis can range from four to nine inches, while penis widths can vary from just over one inch to more than two inches. The Durex study also found that 50% of the almost 3,000 survey respondents felt that the condoms they regularly used did not fit properly; 25% said the condoms were "too tight," 10% said they were "much too tight," and 15% responded that the condoms were "too loose" or "much too loose." Not surprisingly, 42% of those surveyed indicated that condoms should be "better shaped." A whopping 44% of those surveyed reported they had experienced condom slippage or breakage problems in the past. The Durex study concluded, "Given the wide range of penis sizes and the relatively narrow range of condoms designed to fit them, it is perhaps unsurprising to find that 50% of respondents felt that the condoms they use did not fit them properly”. The answers provided also indicate that condoms which don't fit properly are more likely to break during use..." Another study performed by La Trobe University in Australia examined the effect of penis dimension on the probability of complete condom slippage and/or condom breakage in actual use. A total over the course of the study, 16% of the men experienced at least one instance of breakage and 19% experienced complete slippage. The study concluded that condom breakage was strongly associated with penis circumference, particularly for men with above-average girth. In fact, each additional centimeter of penis circumference beyond the average 13.19 cm increased the risk of breakage by 50-100%. Like the Durex study, the researchers concluded, "This finding suggests a need to increase either the range of condom sizes currently available or the [girth] of currently available condoms.” of 3,658 condoms were used by 184 men. ERECTION REJECTION It is no secret that many men dislike wearing condoms. Some Men say that condoms interfere with sex, "get in way," or "kill the mood." Most of the time however, these problems arise because the man has difficulty putting on the condom, or is concerned that the darn thing may slip off. If a condom is difficult to put on due to size issues, the little soldier may suddenly be unable to stand at attention. A survey conducted by the University of Sydney, Australia found that two-thirds of the men surveyed reported they "sometimes" or "often" lost their erection while trying to put on a condom. Of course without an erection, a condom is impossible to put on at all. While many men struggle to put on ill-fitting condoms that are too small, many others experience anxiety that the condom may slip off their slimmer girth. This anxiety can also interfere with the ability to keep the flag at full mast. Condoms that are too loose increase the odds of slippage or leakage. Paradoxically, one of the most common reasons condoms slip off is because they are too tight or too long — if not fully rolled down, the ring at the base can enter the man's partner and be dragged off. Condoms that are too short also increase the risk of exposure to STDs. When condoms are too tight, breakage and slippage is more likely to occur, and sensitivity can be significantly diminished. The reality is that condom size is very important. Unfortunately, unlike penises, most condoms around the world today are made in a very narrow range of sizes. In fact, the overwhelming majority of condoms does not refer to size at all, and simply are marketed as a "one size fits all" product. While a few companies like Trojan have shown some sensitivity to the size issue by producing some larger sized models, very few such products exist, and even fewer are available for those needing a snugger fit. Millions of men continue to struggle with the "one size fits all" mentality that the condom manufacturers apply to condom size, often leading to very unfortunate results. Given the inherent difficulties in measuring customers to ensure a more tailored condom fit, condom producers simply continue to force round pegs into square holes. That’s why to fit a condom effectively and snugly, you have to up your size. Visit Penile Enlargement Blog For More Advice. penis enhancement tip penis enargement surgeries do penis enlargment pills work natural penile enlargment exercise penis enargement forum herbal penis elargement pills penis enlargement surgery cost truth about penile enlargement pills penis enhancement tip
With Merkal in West Germany being pragmatic by pushing through benefit reforms and the big German companies pushing the unions to agree new conditions in exchange for jobs to remain in Germany and respond to Globalisation by moving production to low cost Eastern European or Asian countries. These conditions covered both working practices and redundancy benefits payable. In Germany it appears to be working, with the increase in output and the only country in socialist Europe. Now it’s the turn of France and the French have to look at Germany and see the changes they need to implement. Royal [1] is very likeable and it would be interesting to see the second largest European country with a female President. Can Merkal be the model for Royal to follow and therefore change to being a right wing socialist. The French have to wake up and see that Globalisation is something they must respond to if they are going to survive and not set the other socialist countries of Europe down the wrong road. The enlargement of the European Union [2] with the Eastern European countries will for them be an easy change from communist to socialist. The problem now is that their move to Western Europe will cause earlier immigrants and part-time low cost British workers to lose out to them accepting low wages. But when they stay it will turn and they will seek hire wages, the problem is how long will this take ! in India about two to three decades, now that the Rupe is level with the US dollar. More drain on the UK benefit system will make it collapse. In the European Union there are more socialist countries and governments than conservative or right wing socialist and we now have the mainly Washington DC neo-cons trying to change views throughout the Europe. At least with Germany as the model the rest can hopefully be led. Without change the European Union will be dragged down by the non-producing member countries, like the recent new members. France will have to face Globalisation [3] and change like Germany and not be like most of Europe and try to protect themselves from China and India and other Asian countries. The recent article on Globalisation covers some very hard points and should make everybody in Europe sit up and think about how they are going to survive. European countries without change are now facing very hard times. In the UK demographics have made the government bring in a anti-age law to prevent employers from rejecting older workers and try to ease the skills shortage and is a form of response to Globalisation. Under the labour government socialist reforms have to stop and the unions have to face up to changes like those in Germany, although they are weaker in the UK, they are strong with government employees and transport and telecommunications employees. But that is changing and e-Government is marching forward. The Internet is now the Globalisation tool allowing people to work from any location in the world that telecommunications and satellites allow. Its also the tool of change and will be the driving force for that and enable debate on issues that now affect all of us in the World [4]. [1] FT Magazine October 21/22 2006, Liberté, égalité, féminité by John Thornhill [2] FT Magazine October 21/22 2006, A most unhappy union, review by Quentin Peel [3] FT Magazine October 14/15 2006, Profits of doom by Richard Tomkins [4] Welcome to the Project for the New American Century penis enlargment tip enlarement free penis pills sample penis enlagement patch vimax best penis enlargement surgery pro solution pills review natural pennis enlargement pills vimax does penis enlargement work penis enlagement photo penis enhancement tip
Believe it or not, there is a natural ingredient from Europe that can help change the way your legs feel and the way you feel about the circulation in your legs. Whether we realize it or not, the circulation in our legs can have a huge influence on how we feel and what we do everyday and perhaps even more so every evening. The comfort level of our legs, or better said, their discomfort level at the end of the day can adversely affect our social life and fitness activities - not to mention adversely affecting our sleep. If our legs felt better perhaps we would find it easier to do the things we'd love to do, but find it so difficult to muster the motivation. As if the way our legs can feel at the end of day isn't challenging enough, the changes in the circulation in our legs as we age can seem even more hopeless and discouraging. Now add to that the seeming conspiracy among fashion designers to have us exposing even larger portions of our aging legs and we have a problem that over 80 million Americans with varicose veins understand all too well. (1). Unfortunately, about half of all American women will develop varicose or spider veins at some point in their lives (2). Not only are they unsightly, these leg problems can also cause significant discomfort. Typically, varicose veins are characterized by bulging, blue, sometimes painful and inflamed veins that appear primarily in the calves and thighs. Spider veins, on the other hand, show up as a web of fine lines that can make your legs look like a road map. While age and heredity play a role in the development of varicose and spider veins, weight gain, pregnancy, menopause and the use of hormone replacement therapy can also trigger these vein problems. Making matters worse, chronic inactivity, standing for long periods of time or habitually crossing your legs can make you more prone to injured veins (2). Conventional treatments include surgical stripping, injecting the veins with a chemical irritant or zapping them with lasers. While these approaches can remove existing varicose or spider veins, they will not prevent new ones from developing, since these high-tech treatments do not address the underlying problem of poor circulation. Worse yet, these procedures can also cause infection, scarring, nerve damage and pain (26). If these radical treatments are not an option for you, you'll be happy to hear that there is a natural approach that not only improves the appearance of these ropy, bulging veins, it also fosters leg health to prevent future problems. Veins Explained To understand how varicose veins develop, you need to know a little bit about how blood moves through the body. Essentially, there are two types of major circulatory vessels in the body: the arteries, which channel blood from the heart to the extremities, and the veins, which bring blood from the extremities back to the heart. Of all the veins in your body, leg veins work the hardest to carry blood back to the heart. To accomplish this difficult task, your legs are equipped with specially designed one-way valves that keep the blood moving in the right direction. As efficiently as these valves work, your legs still fight a constant battle against the natural pull of gravity. If the veins can't move the blood efficiently or the one-way valves that prevent the blood from backwashing fail to close properly, blood collects in the legs. This pooling of blood then stretches the vein, causing swelling and injury to the vein's walls (3). Depending on the extent of the enlargement, these veins can show up as either spider or varicose veins. Spider veins are broken capillaries and small veins that appear as jagged red, blue or purple lines on the surface of the skin. While they aren't painful, they can be extremely unattractive. Varicose veins, on the other hand, are thick veins that run deeper beneath the skin. They are far larger and much less attractive than spider veins - and they can make your legs feel fatigued, heavy, achy or even itchy. Varicose veins can also cause burning, throbbing, cramping and restlessness. While these conditions aren't usually dangerous, severe cases can lead to chronic venous insufficiency - a persistent inability of the leg veins to adequately return blood back to the heart (4). Varicose veins are also associated with the development of skin ulcers or a chronic inflammation of a vein - a condition known as phlebitis. Phlebitis is often accompanied by formation of a blood clot, a dangerous situation since the clot can move from the leg vein and travel to the lungs (2). Get a Leg Up with Diosmin Your strategy for battling vein problems naturally is twofold: improving circulation and strengthening the vein walls. The first and simplest measure to improve blood flow is to counteract gravity. Standing or sitting all day makes it harder for blood to move up from the legs and back to the heart. But taking a few minutes to rest with your legs higher than your heart each day allows gravity to help return blood to the heart. Getting in shape can also help relieve varicose and spider veins - and it can even prevent new ones from forming. As we age we lose muscle tone, which adversely affects the health of our legs. Yet adopting a consistent exercise program promotes good circulation and can help to keep our leg muscles, and the blood vessels in our legs, toned. Walking, weight training, low-impact aerobics and swimming strengthen the legs and circulatory system, and help to reduce the throbbing and aching often associated with varicose veins. What you eat can also ease unsightly veins. A low-fat diet filled with fruits, vegetables, beans, legumes and whole grains add key nutrients and fiber to your diet. Eating a fiber-rich diet reduces the chances of constipation which can contribute to varicose veins. Constipation restricts the blood as it returns to the torso through the deep veins in the legs. Straining to have a bowel movement closes off the deep veins in the legs and restricts the flow of blood as it returns to the torso. As the blood backs up, it takes another course through superficial veins, thus the blue streaks in the legs. Eating a fiber-rich diet alleviates and prevents constipation, helping to avoid the damage to the vascular system that can result. In addition to fiber, a diet high in fruits and vegetables also ensures adequate intake of nutrients and phytonutrients, which also help tonify the blood vessels. As a bonus, a healthy diet and exercise program can also jump-start weight loss - an important consideration since carrying too much weight creates extra pressure on your heart and blood vessels, interfering with healthy circulation (2). To strengthen the veins themselves, take a tip from the Europeans. From Austria to France to Italy, women and their doctors have relied on Diosmin for more than 30 years to treat circulatory problems affecting the legs - and with good reason. Diosmin is a unique bioflavonoid derived from citrus fruits and is closely related to other citrus bioflavonoids such as hesperiden, quercetin, and rutin (5). Clinical trials have shown that Diosmin is highly effective in boosting circulation and strengthening the veins in the legs (5). Not only does this improve existing varicose and spider veins, it can also reduce the likelihood of future problems. What makes Diosmin so amazing is its power to specifically target the blood vessels in the legs. Diosmin improves both blood vessel elasticity and microcirculation while relieving pain and inflammation by inhibiting pro-inflammatory prostaglandins and thromboxanes (21,24). Because of its direct action on the integrity of vein walls, Diosmin also reduces the amount of fluid that leaks out of them (21,22). Diosmin's protective benefits do not stop there. Because it is a potent anti-oxidant, Diosmin decreases lipid peroxidation and reduces free radical damage that can undermine vein health (23, 27). In one clinical trial, people who suffered from pain and swelling due to varicose veins experienced significant improvement in their symptoms after taking Diosmin for a few months (6). A review of studies also found that, among more than 5,000 patients with vein disorders, the vast majority not only saw a reduction in their discomfort, they actually saw the swelling in their calves and ankles disappear (7). Across the board, research shows that a daily dose of 500 to 1,000 mg of Diosmin improves the health of leg veins and brings tremendous relief from pain, night cramps and leg heaviness (8,9,10,11). Both short- and long-term use of this highly effective natural ingredient comes without any side effects. It is also so safe that you need not worry about adverse interactions of Diosmin with drugs, foods, lab tests or interactions with diseases or conditions. (5). Help for Hemorrhoids Because Diosmin reduces swelling and bolsters vein health, it can also help people suffering with hemorrhoids - those uncomfortable varicose veins that form in the lower rectum and anus. Along with making it painful to sit, hemorrhoids can itch, bleed or protrude - and almost half of all Americans suffer from them by the time they turn 50 (12). Extensive research conclusively shows that Diosmin can safely alleviate the pain, inflammation and bleeding of hemorrhoids (13,14,15). Best of all, it offers quick relief, often working its magic within a week or two (16). Plus, Diosmin reduces the risk of a relapse (17). Diosmin for Cancer? While no one questions Diosmin's efficacy for treating varicose and spider veins or hemorrhoids, scientists have begun exploring other ways this potent flavonoid may boost health. Their main focus - cancer prevention - especially oral and skin cancers. Researchers haven't conclusively identified the cancer-fighting component in Diosmin, but preliminary experiments show that this flavonoid inhibits the proliferation of cancer cells (18). In two studies pitting Diosmin against other flavonoids like rutin, grapeseed extract and red wine, Spanish investigators found that Diosmin was considerably more effective at reducing the number of metastatic melanoma cells (a potentially deadly type of skin cancer cells that spread through the body) than any of the other flavonoids tested (19,20). Other studies have found that Diosmin puts the brakes on the spread of cancer cells in the mouth (25). Although it could be years before science conclusively proves Diosmin's cancer benefit, this nutrient can't be beat for supporting vein health. Along with taking supplemental Diosmin, there are several simple strategies you can employ to encourage healthy circulation. Eating a high-fiber, anti-oxidant rich diet and getting plenty of exercise can help keep veins in top form. And remember to take a break and put your feet up every now and again. References: 1. American Society for Dermatoloic Surgery. 2. National Women's Health Information Center. U.S. Department of Health & Human Services. 3. American College of Phlebology. 4. Society for Vascular Surgery. 5. Diosmin Monograph. Alternative Medicine Review. 2004;9(3):308-311. 6. Ting AC, et al. Clinical and hemodynamic outcomes in patients with chronic venous insufficiency after oral micronized flavonoids therapy. Vascular Surgery. 2001;35(6):443-447. 7. Ramelet AA. Daflon 500 mg: symptoms and edema clinical update. Angiology. 2005;56 Suppl 1:S25-S32. 8. Bergan JJ. Chronic venous insufficiency and the therapeutic effects of Daflon 500 mg. Angiology. 2005; 56 Suppl 1:S21-S24. 9. Nicolaides AN. From symptoms to leg edema: efficacy of Daflon 500 mg. Angiology. 2003;54 Suppl 1:S33-S44. 10. Smith PC. Daflon 500 mg and venous leg ulcer: new results from a meta-analysis. Angiology. 2005; 56 Suppl 1:S33-S39. 11. Jantet G. Chronic venous insufficiency: worldwide results of the RELIEF study. Reflux assessment and quality of life improvement with micronized Flavonoids. Angiology. 2002;533:245-256. 12. National Institutes of Health. 13. Lyseng-Williamson KA, et al. Micronised purified flavonoids fraction: a review of its use in chronic venous insufficiency, venous ulcers and haemorrhoids. Drugs. 2003;63(1):71-100. 14. Meshikhes AW. Daflon for haemorrhoids: a prospective, multi-centre observational study. Surgeon. 2004;2(6):335-338. 15. Kecmanovic D, et al. PHLEBODIA (diosmine): a role in the management of bleeding nonprolapsed hemorrhoids). Acta Chirurgica Iugoslavica. 2005;52(1):115-116. 16. Diana G, et al. Activity of purified diosmin in the treatment of hemorrhoids. La Clinica Terapeutica. 2000;151(5):341-344. 17. Misra MC, et al. Randomized clinical trial of micronized flavonoids in the early control of bleeding from acute internal haemorrhoids. British Journal of Surgery. 2000;87(12):1732-1733. 18. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042. 19. Martinez C, et al. Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin. Journal of Agricultural and Food Chemistry. 2005;53(17):6791-6797. 20. Martinez C, et al. The effect of the flavonoids dioxmin, grapeseed extract and red wine on the pulmonary metastatic B16F10 melanoma. Histology and Histopathology. 2005;20(4):1121-1129. 21. Ramelet AA. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001;52 Suppl 1:S49-56. 22. Cyrino FZ, et al. Micronization enhances the protective effect of purified flavonoidsfraction against postischaemic microvascular injury in the hamster cheek pouch. Clinical and Experimental Pharmacology & Physiology. 2004;31(3):159-162. 23. Bergan JJ, et al. Therapeutic approach to chronic venous insufficiency and its complications: place of Daflon 500 mg. Angiology. 2001;52 Suppl 1:S43-7. 24. Katsenis K. Micronized purified flavonoids fraction (MPFF): a review of its pharmacological effects, therapeutic efficacy and benefits in the management of chronic venous insufficiency. Current Vascular Pharamcology. 2005;3(1):1-9. 25. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042. 26. National Women's Health Information Center. U.S. Department of Health and Human Services, Office on Women's Health. 27. Villa P, et al. Protective effect of diosmetin on in vitro cell membrane damage and oxidative stress in cultured rat hepatocytes. Toxicology. 1992;73:179-189.